Next to Normal is a rock musical with book and lyrics by Brian Yorkey and music by Tom Kitt. Its story concerns a mother who struggles with worsening bipolar disorder and the effect that her illness has on her family. The musical also addresses such issues as grieving a loss, suicide, drug abuse, ethics in modern psychiatry, and suburban life.

The musical won 2009 Tony Awards for Best Original Score for Tom Kitt (music) and Brian Yorkey (lyrics), Best Orchestration for Michael Starobin and Tom Kitt, and Best Performance by a Leading Actress in a Musical for Alice Ripley. The show was nominated for a total of 11 Tony Awards, including Best Musical. Next to Normal received several workshop performances before it debuted off-Broadway in 2008, winning the Outer Critics' Circle Award for Outstanding Score and receiving nominations for Drama Desk Awards for Outstanding Actress (Alice Ripley) and Outstanding Score. It then played at the Arena Stage in Crystal City, VA from November 2008 to January 2009 and opened on Broadway in April 2009.

Next to Normal began previews on Broadway at the Booth Theatre on March 27, opening on April 15, 2009. The cast from the Arena Stage production returned as well as the director, Greif. The musical was originally booked for the 1,096-seat Longacre Theatre, but, according to producer David Stone, "When the Booth Theatre became available... we knew it was the right space for Next to Normal".

Reviews were favorable. Ben Brantley of the The New York Times wrote that the Broadway production is "A brave, breathtaking musical. It is something much more than a feel-good musical: it is a feel-everything musical." Rolling Stone Magazine called it "The best new musical of the season – by a mile." Next to Normal was on the Ten Best of the Year list for 2009 of "Curtain Up".

Next to Normal set a new box office record at the Booth Theatre for the week ending January 3, 2010, grossing $550,409 over nine performances. The previous record was held by the 2006 production of Brian Friel's Faith Healer with a gross of $ 530,702.

In early May 2009, about six weeks into the Broadway Production, Next to Normal began publishing an adapted version of the show over Twitter, a social media network. Over 35 days, the serialized version of the show was published in the form of tweets, short messages utilized by Twitter, a single line from a character at a time. The Twitter performance ended the morning of June 7, 2009, the morning of the 2009 Tony Awards.

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